REVOLUTIONIZING THE FUTURE OF NEW DRUG DISCOVERY: USE OF A.I. BY INDUSTRY GIANTS AND CASE STUDY OF ABBVIE
DOI:
https://doi.org/10.56362/Rev23101011SKeywords:
A.I. in drug discovery, pharmaceutical industry, target identification, drug screening, clinical trial optimizationAbstract
A.I. has revolutionized the drug discovery process by enabling researchers to analyze vast amounts of data and generate insights that would be difficult for humans to identify. A.I. is used in various applications such as target identification, drug screening, drug optimization, and clinical trial design and execution. This has led to more effective drugs and better patient outcomes. The use of A.I. in drug discovery is expected to increase in the coming years. This paper provides an analysis of the top 27 Pharma companies giants, along with a case study of Abbvie Inc. on their use of A.I. in the pharmaceutical industry.
References
Berg Health. (n.d.). Clinical trial A.I. Accessed March 12, 2023, https://berghealth.com/clinical-trial-ai/; BenevolentAI. (n.d.). Another discovery. Accessed March 12, 2023. https://www.benevolent.com/approach/drug-discovery.
Exscientia. (n.d.). Another discovery. Accessed March 12, 2023. https://www.exscientia.ai/drug-discovery/
Insilico Medicine. (n.d.). Another discovery. Retrieved March 12, 2023, from https://insilico.com/drug-discovery; Mendel.ai. (n.d.). Accelerating clinical trials with A.I. Accessed March 12, 2023, from https://www.mendel.ai/solutions/clinical-trials.
Forbes. (2021). The World’s Largest Public Companies. Pharmaceutical & Biotech Industry. Forbes Global 2000. Accessed March 13, 2023. https://www.forbes.com/global2000/list/#header:pharma-biotech.
Duch, W. et al. (2007) Artificial intelligence approaches for rational drug design and discovery. Curr. Pharm. Des. 13, 1497–1508.
Henstock, P. Artificial intelligence for Pharma: Time for internal investment. Trends in Pharmacological Sciences, August 2019, Vol. 40, No. 8.
Alsevar, J. Medicine by Machine. Fortune. February 2020.
DiMasi, J.A. et al. (2016) Innovation in the pharmaceutical industry: new estimates of R&D costs. J. Health Econ. 47, 20–33.
Lamberti, M. et al. A Study on the Application and Use of Artificial. Intelligence to Support Drug Development. 2019 Elsevier.
Lamberti, M. et al. A Study on the Application and Use of Artificial. Intelligence to Support Drug Development. 2019 Elsevier.
Ranganathan, A., & Ong, W.K. (2020). The Role of Artificial Intelligence in Drug Discovery. Clinical and Translational Medicine, 10(4), e186. https://doi.org/10.1002/ctm2.186 ; Aspuru-Guzik, A. (2021). Artificial intelligence and the future of drug discovery. Journal of Medicinal Chemistry, 64(14), 9075-9076. https://doi.org/10.1021/acs.jmedchem.1c01080; Ma, J., Sheridan, R.P., Liaw, A., Dahl, G.E., Svetnik, V., & DeepChem Development Team. (2019). Deep learning enables rapid identification of potent DDR1 kinase inhibitors. Nature Biotechnology, 37(9), 1038-1040. https://doi.org/10.1038/s41587-019-0224-x
Stamenovic, M. Data analysed and provided as source for the table by the author.
About AbbVie. AbbVie. Accessed March 13, 2023. https://www.abbvie.com/about-us/overview.html.
Abbvie Reports Fourth-Quarter and Full-Year 2020 Financial Results.” AbbVie. Accessed March 13, 2023. https://www.abbvie.com/newsroom/news/abbvie-reports-fourth-quarter-and-full-year-2020-financial-results.html.
AbbVie. (2022, February 4). AbbVie Reports Full-Year and Fourth-Quarter 2021 Financial Results (Press release). https://news.abbvie.com/news/press-releases/abbvie-reports-full-year-and-fourth-quarter-2021-financial-results.htm
Insilico Medicine and AbbVie collaborate to accelerate drug discovery for age-related diseases.” Insilico Medicine. Accessed March 13, 2023. https://insilico.com/press-releases/insilico-medicine-and-abbvie-collaborate-to-accelerate-drug-discovery-for-age-related-diseases.
A.I. specialist Cyclica partners with AbbVie on drug discovery.” PMLive. Accessed March 13, 2023. https://www.pmlive.com/pharma_news/ai_specialist_cyclica_partners_with_abbvie_on_drug_discovery_1297745. AbbVie and Biocorpora sign drug discovery collaboration. European Pharmaceutical Review. Accessed March 13, 2023. https://www.europeanpharmaceuticalreview.com/news/121633/abbvie-and-biocorpora-sign-drug-discovery-collaboration/
